Buy 4-Cl-PVP Crystal | 4mmcchems – Premium Research Chemical.

Introduction to 4-Cl-PVP Crystal

4-Cl-PVP (4-Chloro-α-pyrrolidinovalerophenone), also known as 4-chloro-α-PVP or 4C-PVP, is a synthetic cathinone belonging to the pyrrolidinophenone class of compounds. It is the para-chlorinated analogue of α-PVP, distinguished by the substitution of a chlorine atom at the 4-position of the phenyl ring . This structural modification produces a compound with distinct pharmacological properties compared to its parent molecule.

The compound was first synthesized in the 1960s and has recently re-emerged as a novel psychoactive substance detected in forensic casework across the United States and Europe . As a research chemical, 4-Cl-PVP is primarily utilized as a certified reference material for forensic and analytical applications, including GC-MS and LC-MS method development and quality control . At 4mmcchems, we supply premium-grade 4-Cl-PVP Crystal to researchers and professionals worldwide, with a focus on fast, discreet shipping across Europe.

Product Specifications

Product Name: 4-Cl-PVP Crystal (4-Chloro-α-pyrrolidinovalerophenone)

Synonyms: 4-chloro-α-PVP, 4C-PVP, 4′-chloro-α-pyrrolidinopentiophenone

CAS Number: 5881-77-6 (free base); 5537-17-7 (hydrochloride salt)

Molecular Formula: C₁₅H₂₀ClNO · HCl

Molecular Weight: 265.78 g/mol (free base); 302.20 g/mol (HCl salt)

Purity: ≥ 98% (verified by third-party HPLC/GC-MS testing)

Form: Crystalline solid

Storage: -20°C for long-term stability

Availability: In stock, ready for immediate dispatch

Chemical Properties and Mechanism of Action

4-Cl-PVP acts as a potent inhibitor of the dopamine transporter (DAT) and norepinephrine transporter (NET), with negligible activity at the serotonin transporter (SERT). Research demonstrates that 4-Cl-PVP has the capacity to inhibit DAT and NET, similar to other pyrovalerone-type cathinones .

Key Pharmacological Data

• Mechanism: Norepinephrine-Dopamine Reuptake Inhibitor (NDRI)

• DAT Inhibition: Potent inhibition, consistent with other α-PVP analogues

• Reinforcing Potency: Rank order of α-PVP > METH > 4-Cl-α-PVP > 4-Cl-α-PPP, demonstrating significant abuse potential

• Discriminative Stimulus Effects: 4-Cl-α-PVP fully and dose-dependently substitutes for methamphetamine, with approximately 3-fold lower potency than METH

• Duration of Action: Psychostimulant effects lasting more than 60 minutes at higher doses

Metabolic Profile

Research has identified the metabolic pathways of 4-Cl-PVP, including Phase I metabolites formed through ketone reduction and Phase II metabolites . The chlorine isotopic pattern is key for identification in analytical testing .

Research Applications

4-Cl-PVP is valuable for studying dopamine transporter dynamics, structure-activity relationships within the cathinone class, and comparative pharmacology of psychostimulants. It also serves as an analytical reference standard for identifying this compound in forensic samples, including biological matrices .

Why Choose 4mmcchems?

1. Uncompromising Quality

We source our 4-Cl-PVP Crystal from certified manufacturers with strict adherence to Good Manufacturing Practice (GMP) guidelines. Every batch undergoes independent HPLC and GC-MS testing to guarantee purity and potency, meeting the ≥98% purity threshold required for analytical reference materials .

2. Discreet and Secure Packaging

Your privacy is paramount. All orders are shipped in plain, unbranded packaging with no external markings indicating contents. Tamper-evident seals ensure security throughout transit.

3. Worldwide Shipping with European Focus

4mmcchems operates a robust global logistics network. We offer fast, reliable shipping to customers worldwide, with a particular emphasis on European markets:

• European Shipping: 4-Cl-PVP is a regulated substance in multiple European jurisdictions. Germany has classified it under the NpSG (New Psychoactive Substances Act) for industrial and scientific use only . The United Kingdom lists it as a Class B substance. We have optimized shipping routes to ensure timely delivery to all EU member states, the UK, Switzerland, and more.

• Fast Transit Times: Typical delivery to European destinations ranges from 3 to 7 business days.

• Tracking Provided: Every order comes with a tracking number for real-time shipment monitoring.

4. Competitive Pricing and Bulk Discounts

We offer tiered pricing for bulk orders, making 4mmcchems the cost-effective choice for large-scale research projects. Contact our sales team for custom quotes.

5. Responsive Customer Support

Our knowledgeable team is available to answer queries regarding product specifications, shipping, and order status. We prioritize clear and prompt communication.

Safety and Regulatory Information

4-Cl-PVP is a regulated substance in many jurisdictions globally. It is classified as a Schedule I controlled substance in the United States . In Sweden, it is controlled under the Narcotics Act (Lag 1992:860) . The compound has been associated with serious adverse health effects including violent behaviors, emergency department admissions, and potential fatalities .

Important Considerations for Researchers:

• Controlled Status: 4-Cl-PVP is a controlled substance in many countries. It is the customer’s responsibility to verify the legal status of this product in their jurisdiction before placing an order.

• Research Use Only: This product is intended for research, forensic, and analytical applications only. Not for human or veterinary use .

• Handling Precautions: Standard laboratory safety protocols should be followed when handling this compound. Appropriate personal protective equipment (PPE) is recommended.

Shipping Information: Worldwide Delivery

4mmcchems is committed to making our products accessible globally. We ship to all major regions, including:

• Europe: All EU member states, UK, Switzerland, Norway, and more.

• North America: USA, Canada, Mexico.

• Asia: Japan, South Korea, Singapore, China, India, and others.

• Australia & Oceania

• South America

• Middle East & Africa

Shipping Methods:

• Standard Air Mail (7-21 days, tracking available)

• Express Courier (3-7 days, fully tracked, signature required)

Customs and Duties: Customers are responsible for any customs duties or import taxes applicable in their country. We provide all necessary documentation to facilitate smooth customs clearance, subject to local regulations.

How to Order

1. Browse Our Catalog: Select 4-Cl-PVP Crystal and add to cart.

2. Checkout: Fill in your shipping details and choose your preferred payment method.

3. Payment: We accept cryptocurrencies and bank transfers for secure transactions.

4. Confirmation: Receive an order confirmation with tracking details upon dispatch.

Frequently Asked Questions

Q: What is 4-Cl-PVP used for in research?

A: 4-Cl-PVP is used as an analytical reference material for forensic and analytical applications, including GC-MS and LC-MS testing methods, transporter binding assays, and neuropharmacological studies .

Q: Is 4-Cl-PVP legal to purchase?

A: 4-Cl-PVP is a controlled substance in many countries, including the US (Schedule I) and Sweden . It is the customer’s responsibility to verify the legal status of this product in their jurisdiction before placing an order.

Q: How should 4-Cl-PVP be stored?

A: Store at -20°C for long-term stability. Protect from light and moisture .

Q: What if my order is seized by customs?

A: While we take every precaution to ensure successful delivery, we cannot guarantee customs clearance in all countries, especially given the controls on 4-Cl-PVP. Please refer to our shipping policy for more details.